A suburban Chicago family travels across the United States and encounters a series of disasters; when the Griswolds win a two-week vacation in Europe they have no idea the havoc they will create; the Griswolds have a series of comedic adventures when they spend their family vacation in Las Vegas.

When Clark Griswold (Chase) puts his mind to something, we soon realize he hasn't got one. Still, nothing stops him when the vacation bug hits. This time, he's chosen Las Vegas, the new family entertainment capital of America!